UNVEILING CHALLENGES IN REAL-TIME PCR STRATEGIES FOR DETECTING TREATMENT FAILURE: OBSERVATIONS FROM CLINICAL TRIALS ON CHRONIC CHAGAS DISEASE

Unveiling challenges in real-time PCR strategies for detecting treatment failure: observations from clinical trials on chronic Chagas disease

Chagas disease (CD) caused by Trypanosoma cruzi remains a Neglected Tropical Disease with limited access to diagnosis and treatment, particularly for chronically infected patients.Clinical trials are underway to improve treatment using new drugs or different regimens, and Real-Time PCR is used to assess the parasitological response as a surrogate b

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